"Motilium" during pregnancy: indications, instructions for use, reviews

2024 Author: Priscilla Miln | [email protected]. Last modified: 2023-12-16 00:21

Digestive disorders during childbearing are very common. After all, all the organs of a woman undergo great changes. This can lead to nausea, vomiting, heartburn, and other discomforts. Undoubtedly, these feelings overshadow the period of bearing a child, and therefore a woman seeks to get rid of them. Can Motilium be used during pregnancy and how should it be used?

What is this drug?

This remedy is known as an antiemetic. Therefore, Motilium is often used for nausea. Due to its pharmacological properties, it exerts pressure on the lower esophageal sphincter, thereby accelerating its emptying. In addition, the drug does not affect the secretion of gastric juice.

Pregnant women who suffer from toxicosis may be prescribed "Motilium" for nausea. However, in this case, it is necessary to take into account the associatedwoman's disease and individual drug tolerance.

Composition of the drug

The active substance of this drug is domperidone. It is a dopamine antagonist and has an antiemetic effect. Therefore, the use of "Motilium" for vomiting is quite effective.

The active substance is also poorly absorbed, so it is difficult for him to cross the blood-brain barrier (BBB). Extrapyramidal side effects are rarely observed from taking this medicine. However, it has been noted that domperidone affects the production of prolactin by the pituitary gland.

In addition to domperidone, Motilium contains lactose monohydrate, corn and potato starch, cellulose, as well as povidone, magnesium stearate, cottonseed oil, sodium lauryl sulfate. The shell of the tablet is hypromellose and sodium lauryl sulfate.

Issue form

Most often the drug is found in the form of tablets. However, the release form of "Motilium" can also be in the form of a suspension. The latter is most often used in the treatment of children.

"Motilium" in tablets is a round biconvex film-coated tablets. The color is usually white or slightly creamy. The tablets have inscriptions: JANSSEN on one side and "M 10" on the other.

Tablets contain 10 mg of active ingredient. They are sold in blisters of 10 or 30 pieces. The package contains one blister and instructions for using the drug.

Suspension"Motilium" is sold in bottles. They come with a dosing pipette. In addition to the active substance domperidone, the composition includes sweeteners, thickeners, water and other components. Precisely because the drug in this dosage form has a sweet taste, it is also called a syrup.

The expiration date of Motilium, like other drugs, is indicated on the package. Usually it is 5 years. After the expiration date, the medication should be disposed of.

What helps?

"Motilium" during pregnancy is prescribed with extreme caution. The medication is indicated for the following conditions:

• flatulence and feeling of bloating;
• digestive disorders accompanied by nausea and vomiting;
• dyspepsia of an organic, infectious or functional nature;
• feeling of heaviness and discomfort in the upper gastrointestinal tract.

Who is contraindicated for?

This drug is not for everyone. There are people for whom it is contraindicated. For example, those who are observed:

• bleeding in the gastrointestinal tract;
• intestinal obstruction;
• liver and kidney disorders of varying severity;
• intolerance to drug components;
• prolactinoma;
• heart failure and underlying cardiovascular diseases.

The instructions for the use of "Motilium" during pregnancy indicate that in the absence of concomitantsymptoms listed above, the use of the drug is allowed. However, it should be taken with caution and only after consulting a doctor.

Pregnancy and lactation period

During pregnancy, "Motilium" helps to get rid of the symptoms of nausea, vomiting and those conditions that may be the result of toxicosis. Due to its poor absorption and inability to accumulate, this drug is sometimes prescribed by doctors to pregnant and lactating women.

"Motilium" during early pregnancy helps to cope with toxicosis. Women who suffer from nausea and vomiting find salvation in this remedy. However, since its effect on the fetus has not yet been fully studied, the use of this medication without a full examination and a doctor's prescription is not recommended.

As for the use of Motilium during late pregnancy, caution is also important here. This drug does not cause serious changes in the body, so it is also not dangerous for the fetus. But every woman, like her child, is individual, so do not neglect the advice of a doctor before taking the drug.

The active substance of the drug is able to penetrate into breast milk. However, its concentration in it is extremely low. Since it has not been fully studied whether domperidone harms the body of a newborn child, it is recommended to take the drug only if the expected benefit to the mother is greater than the potential risk to the fetus. Also in the instructions for use it is written that it is better for mom to refusebreastfeeding while taking medication.

It can be said that taking "Motilium" during pregnancy and lactation is a purely individual matter for each woman. But still, self-medication can only harm the mother and child, so medication should be carried out under the strict supervision of specialists.

Dosage and regimen

"Motilium" during pregnancy, as in other conditions, has a certain dosage regimen and method of application. It is better to take it before meals, because after eating, the absorption of the active substance worsens.

For adults and children over 12 years of age and weighing more than 35 kg, it is recommended to take 4 tablets of 10 mg per day. That is, the daily dose of the drug is 40 mg. 3 tablets to be taken during the day and 1 at bedtime.

Initially, the drug is taken for a month. After this period, you need to reassess your condition and, if necessary, conduct an examination. The doctor will either recommend that you continue taking Motilium or stop it, possibly replacing it with another drug.

It is important to draw your attention to the fact that the duration of taking the drug without a doctor's prescription should not exceed two weeks. If you suddenly missed the time of taking the medication, then you should not use a double dose during the next dose. It is enough just to continue taking the pills according to the established scheme.

Not recommended for children under 12give the drug in the form of tablets. Especially for the treatment of pediatric patients, the suspension "Motilium" is provided. It must be given to the child strictly at the same time. The amount of the drug given at one time depends on the condition of the child and his body weight. These nuances are spelled out in the instructions for use.

With acid reflux (in the common people - heartburn), the drug should be taken half an hour before meals. It is also important to strictly follow the prescribed dosage. For this, a special measuring pipette or syringe is provided.

Side states

Based on pharmacological studies and real reviews of Motilium, a number of possible side effects are listed in the instructions for use. The probable frequency of occurrence of these very adverse human conditions is also indicated. Among them, dry mouth is the most common. This symptom occurs in 1 to 10 percent of people who take the drug.

Rarely, body conditions such as diarrhea, decreased libido, anxiety, sleep disturbances, headaches, rashes, itching or skin irritation, fatigue, increased breast milk production and increased breast sensitivity, reaching the onset of pain in the mammary gland.

Also, urticaria, Quincke's edema (as a manifestation of an allergic reaction to the components of the drug), irritability and nervousness, convulsions and hyperkinesis, tics, increased production of the hormone prolactin, leading to gynecomastia (increasemammary glands in males) or to stop the menstrual cycle in females, problems with urination, arrhythmias, or abnormalities in the liver and kidneys.

Overdose symptoms

Situations of overdose of "Motilium" among adults practically do not occur. While infants and older children are more susceptible to symptoms of drug overdose. Among them, altered consciousness, involuntary muscle contractions, hyperkinesis, tics, disorientation in space and time, sleep disturbances, and various extrapyramidal reactions are often observed.

If you observe symptoms of a severe overdose, then you need to urgently rinse your stomach and take activated charcoal. Most importantly, carry out such manipulations no later than an hour after taking the drug.

"Motilium" for kids

This drug is also effective in the treatment of pediatric patients. Moreover, it can be used almost from birth. In the instructions for using the Motilium suspension for children, indications for taking Motilium in infancy and childhood are frequent and profuse regurgitation, nausea, vomiting, poisoning, constipation and other disorders in the gastrointestinal tract.

Do not forget that self-medication is fraught with serious complications. Therefore, having seen a symptom suitable for you in the indications for use, you should not stuff the child with medicine without a doctor's prescription.

In the instructions for use of the suspension"Motilium" for children is indicated that it must be taken half an hour before the child eats food. Even better, give it to children at bedtime.

If a child has pain or discomfort in the epigastric region, then the dosage of the drug is calculated based on weight. Thus, for every 10 kg of weight, 2.5 ml of syrup is given. In this case, take the drug three times a day.

If your child suffers from nausea and vomiting, then here they give 5 ml of medicine for every 10 kg of body weight. Also before meals or at night.

How long does Motilium last? After half an hour, the drug reaches its maximum concentration. However, the final elimination of symptoms, especially frequent regurgitation, will occur no earlier than 2-3 days after the start of treatment. The course of application of the drug is usually about two weeks.

"Motilium" during pregnancy: reviews

Will the medicine harm the baby? This is the most common question women in pregnancy ask before taking any medication.

"Motilium" does not apply to aggressive drugs that can cause serious changes in the development of the baby. However, it is not recommended for pregnant women to take it without a doctor's prescription. Only a qualified specialist is able to adequately assess the situation, take into account all your individual characteristics and determine the need for drug therapy.

As for the reviews of those who took Motilium, they are enoughpositive. Many people think that doctors will not give bad advice and will not prescribe harmful medicine, especially to a pregnant woman.

Others believe that any medicine is harmful to a woman carrying a child. Therefore, the symptoms of nausea and vomiting, otherwise referred to as toxicosis, are best removed with folk remedies. They advise using s alted crackers, lemon or mint candies for this.

However, almost everyone who has taken this drug talks about its effectiveness. But there is one "but" - this is the price of the drug. It is high enough that makes people look for cheaper analogues.

Price and analogues of "Motilium"

The cost of "Motilium" is quite high, and therefore not everyone can afford it. The price varies depending on the dosage form of the drug. For example, a suspension for children in the amount of 100 ml will cost you 850 rubles. "Motilium" in the form of tablets is somewhat cheaper. If there is one blister in the package, then the drug will cost about 500 rubles, and if there are three, then 800 rubles.

Like any other drug, Motilium has cheaper analogues.

All such medications are divided into two groups: drugs that have the same active ingredient in their composition, and drugs that have the same effect, but consist of other components:

1. "Ganaton" is an analogue of "Motilium", which is also prescribed for disorders of the gastrointestinal tract, vomiting, nausea and bloating. ExceptIn addition, it is also used for colic, loss of appetite and even anorexia. 10 tablets cost 300 rubles. Since this drug contains other medicinal components, side effects and contraindications will be different. For example, this drug is prohibited during pregnancy, lactating women and children under 16.
2. "Brulium Lingvatabs" is also an analogue that helps fight the manifestations of dyspepsia. This is a fairly strong drug, so take it in small dosages. It is contraindicated in small children whose body weight has not reached 35 kg. The price range of the drug is from 120 rubles to 240 rubles.
3. "Motilak" - refers to a group of drugs that have similar active ingredients in their composition. You can find tablets for oral administration and for resorption. Contraindications to this drug are similar to contraindications to Motilium. The only difference between them is that Motilak is not recommended for children weighing less than 20 kg. Motilak costs about 250 rubles.
4. Metoclopramide is the cheapest analogue, one of the drugs that contains other active ingredients in its composition, but performs the same functions as Motilium. The active substance is metoclopramide hydrochloride. The drug is available in two dosage forms: in tablets and in solution for intramuscular and intravenous injections. However, there are restrictions when taking this drug. It is prohibited for people suffering from bronchial asthma, pregnant women, lactating women and for children under three years of age. Pricemedication does not exceed 150 rubles.
5. "Cerucal" is an analogue of the type "Metoclopramide". The active substance and dosage forms of the drug are the same. However, he has more contraindications. Among them are Parkinson's disease, epilepsy, pheochromocytoma, dyskinesia and lactation. Another disadvantage of this drug is the greater number of side effects that can occur when taking it. These include changes in consciousness, hallucinations, and Parkinson's syndrome. It turns out that the low price of the drug does not guarantee its quality. You can buy this analogue at any pharmacy in the price range from 30 to 250 rubles.
6. "Domperidone" is an analogue produced in two forms: "Domperidone Hexane" and "Domperidone Teva". This drug is effective in combating acid reflux, colic and vomiting, and also improves the functioning of the gastrointestinal tract. "Domperidone" is recommended for use in the postoperative period for improving digestion, as well as for hiccups, cholecystitis and to neutralize the negative effects of medications. This medicine has four forms of release: rectal suppositories, tablets, suspensions and a form for oral use. Of the contraindications, infancy, the presence of internal bleeding and intestinal obstruction are added. The price range starts from 100 rubles. This drug is often prescribed during pregnancy. However, it is not recommended for breastfeeding as it reaches as much as 50 percent in breast milk.
7. "Maalox" -prescribed for the treatment of duodenum and stomach, gastritis, flatulence, hyperacidity, bloating and gastroduodenitis. It is the main competitor of Motilium. The drug is contraindicated in people with a lack of phosphorus in the blood and Alzheimer's disease, as well as children under 15 years of age. The price varies depending on the dosage form of release and ranges from 120 to 520 rubles.
8. "Motizhekt" - very similar to "Motilium", but it is prohibited for children under 5 years old who weigh less than 20 kg. A feature of the use of this drug is that it is allowed to use 2 tablets at a time in severe cases, and up to 6 tablets per day. However, there is still a limit - 60 mg per day. The drug is taken 15 minutes before meals for better absorption. In case of an overdose of this drug, arrhythmia, a decrease in blood pressure and sleep disturbances are observed. In such a situation, it is enough to take activated charcoal at the rate of 1 tablet per 10 kg of weight. If an allergic reaction occurs, an antihistamine should be taken. The price for a pack of 30 tablets is approximately 150 rubles.