"Berodual" during pregnancy: instructions for use, indications and contraindications, reviews

2024 Author: Priscilla Miln | [email protected]. Last modified: 2023-12-16 00:21

The drug "Berodual" belongs to the group of bronchodilators with an inhalation type of action. Its active ingredients expand spasmodic bronchi during exhalation. The drug "Berodual" during pregnancy is sometimes simply vital, since intense bouts of bronchospasm can have a negative effect on the body of a woman and a child. While carrying a baby, this remedy is best used in the form of an aerosol, which is allowed from the 12th week of conception.

Features of the drug

A feature of pregnancy is that during this period hormonal changes can occur, which provoke a decrease in immunity. This is a completely natural reaction of the body, which allows you to save the fetus. That is why at this time chronic infectious and inflammatory processes that a woman suffered even before pregnancy are so often exacerbated. These diseases include bronchitis and obstructive pulmonary disease.

During pregnancy, the number of bronchospasms may increase. Respiratory failure adversely affects the body of the mother and child. The lack of oxygen in the mother's body is especially dangerous for the normal development of the fetal brain. That is why frequent bouts of bronchospasm must be removed.

Often prescribed the drug "Berodual" during pregnancy, as it is a combined bronchodilator, which includes two active substances. They contribute to the expansion of the bronchi, but at the same time they act in different ways, enhancing the therapeutic effect of each other. This makes it possible to use small dosages of the drug. At the same time, there is a powerful therapeutic effect and the likelihood of side effects is minimized.

If Berodual is used during pregnancy in a strictly indicated dosage and as prescribed by the doctor, then it usually does not adversely affect the woman and the fetus. This is mainly a topical agent, so it enters the blood in small quantities.

Answering the question whether it is possible to inhale with "Berodual" during pregnancy, it must be said that in this form the medicine is allowed only from the second trimester, since the components included in the composition can suppress the contractility of the uterus, which can lead to violations during childbirth.

Composition and release form

The drug "Berodual" is a complex remedy that has two main components. These components have different therapeutic effects. Among the main effects of the drug, you needhighlight such as:

• antispasmodic;
• anti-inflammatory;
• improves bronchial drainage;
• normalizes the functioning of the respiratory system.

After using Berodual during pregnancy to treat a cold, patients generally report improvements such as:

• breathing easier;
• cough reduction;
• disappearance of wheezing.

The big plus of this drug is that it does not contain hormonal components, so it can not affect the hormonal balance of the body. The drug "Berodual" is available in two dosage forms. The first is vials designed for inhalers. Usually one package of medicine has a volume of 2 ml, which corresponds to 40 drops of the drug. 1 ml of solution contains 500 mg of fenoterol and 250 mg of ipratropium. In addition, the medicinal product contains:

• sodium chloride;
• benzalkonium chloride;
• Edetate disodium dihydrate.

They also produce disposable inhalers with Berodual. The capacity of the drug reservoir is 20 ml, which is equal to 200 injections. This form is very convenient for use by asthma patients, as the inhaler can be carried very conveniently. The composition of the solution for the inhaler includes tetrafluoroethane. Also included are ingredients such as citric acid and ethanol.

The active substance is fenoterol. This component helps to eliminate spasms of the bronchi and small vessels. It also interferes with the activity of histamines, as well as otherprovocateurs of inflammation. This medicine can be used together with other agents that promote faster treatment of bronchial diseases, in particular, such as Lazolvan, Bromhexine, Theophylline. At the same time, the therapeutic effect of fenoterol only increases.

Ipratropium bromide helps to reduce the muscle tone of the bronchi and eliminate their spasm. This substance prevents the narrowing of the bronchi, improves the functioning of the bronchial glands, and also increases the heart rate.

Main drug action

Active inhalation of the Berodual solution normalizes the functioning of the respiratory organs almost immediately, even if approximately 10-39% of the entire inhaled mass is deposited in the tissues. Everything else settles on the walls of the inhaler, as well as in the oral cavity.

The main active ingredient has a pronounced therapeutic effect within 15 minutes after the application of the drug. It consists in forcing exhalation per second, which is considered a very significant parameter for assessing the features of the functioning of the respiratory organs, as well as achieving a peak in the rate of exhalation of air. The maximum effect of the active component is observed 1-2 hours after the use of the drug. It is worth noting that the therapeutic effect is maintained within 6 hours.

Indications for use

The drug "Berodual" during pregnancy is used to treat and prevent the occurrence of chronic obstructive respiratory diseases. This drug is prescribed for:

• asthma;
• bronchitis;
• severe lingering cough.

In addition, according to the instructions, the drug is used in the preparation of the respiratory tract for the subsequent use of various mucolytic agents, corticosteroids or antibiotics by aerosol method.

Using an inhalation canister

The drug "Berodual" during pregnancy in the 1st trimester can only be used as an inhalation spray. To do this, remove the protective cap from the can. If the drug has not been used for more than 3 days, then it is necessary to make sure that it works by making a test press on the can button. If an aerosol cloud appears at the same time, this means that the drug is ready for use.

When using Berodual for inhalation during pregnancy, you must first consult a doctor. How is the procedure carried out? You need to take the deepest possible breath, then wrap your mouth around the tip of the inhaler so that its mouthpiece is located below. Exhale completely. Then lightly press the bottom of the can while taking a deep breath. After using the inhaler, put the protective cap back on it.

During pregnancy, "Berodual" can be used during an acute attack, but for this you need to take 2 breaths. If at the same time relief does not come, then after 5 minutes the procedure can be repeated. If there is no result, you need to consult a doctor, since such a conditioncan be very dangerous.

As a prophylaxis, you can take 1-2 breaths during the day. However, the total number of breaths per day should not exceed eight.

Using mortar

During pregnancy (2nd trimester), Berodual can be used as a solution for inhalation using a nebulizer. This type of inhaler helps turn the healing liquid into a fine cloud that can penetrate even hard-to-reach areas of the respiratory system.

For the preparation of therapeutic liquid, you need to use saline. It is not recommended to use distilled water for this, as it can lead to overdrying of the mucosa and an even greater increase in cough. It is enough to dilute the required dosage of the drug with sodium chloride so that the total volume of the solution is 3-4 ml. In this case, all components for the preparation of the medicinal product must be at room temperature.

After preparing the solution, you can use the drug "Berodual" for inhalation. During pregnancy, this procedure will be a salvation for many women. It is carried out until the nebulizer container is empty. Steam should be inhaled through the mouth and exhaled through the nose. The pace should be as comfortable as possible. The duration of the procedure should be no more than 7 minutes. The residue remaining after dilution of the drug is not subject to further use.

Application of "Berodual N"

The use of this form of the drug is no different from the usual drug. Reinforced variantIt is produced in the form of an aerosol in special bottles. It can also be diluted with saline and added to an inhaler. Is it possible to breathe "Berodual" during pregnancy - only the doctor decides after the examination. Self-treatment is unacceptable, as this can lead to a deterioration in well-being.

Will it harm the fetus

Many people are wondering if Berodual can be used during pregnancy and how safe this drug is. It is worth noting that the drug can provoke side effects from the cardiovascular system, which manifests itself in the form of heart rhythm disturbances, heart palpitations, and increased pressure.

It is possible to use Berodual for inhalation during pregnancy only with the permission of an obstetrician-gynecologist or a therapist in a antenatal clinic. If there are contraindications, in particular, such as toxicosis or high blood pressure, it is better to replace it with another drug that has fewer side effects.

Answering the question whether Berodual can be used during pregnancy, it must be said that it is not recommended to use this drug for women suffering from heart disease with a violation of its rhythm, as well as with increased sensitivity of the body to the components of the drug. With caution, the drug is prescribed for increased intraocular, arterial pressure, ischemia, angina pectoris, diabetes mellitus. In addition, it is not recommended for use after a heart attack, with increased thyroid function, bladder obstruction, and the formation of viscous mucus in the bronchi.

Berodual is prescribed with extreme caution for inhalation during pregnancy in the 1st trimester, as it can have a relaxing effect on the muscles of the uterus, which can lead to difficulty during childbirth. In addition, this remedy, like any other inhalation drug, can provoke an even greater increase in bronchospasm. In this case, it must be replaced under the supervision of a physician.

Regular use of high doses of the drug to relieve obstruction can provoke an uncontrolled worsening of the course of the disease. In this case, to prevent the development of complications, it is necessary to change the treatment plan. The drug "Berodual" when planning pregnancy and during the bearing of the baby should be used only under the supervision of a doctor.

Contraindications

It is far from always possible to use Berodual during pregnancy, as there are certain contraindications for the use of this drug. It is worth remembering that this is a potent medicine, so it is not recommended to use it for certain diseases.

First of all, this applies to people with diseases of the cardiovascular system, in particular, such as cardiomyopathy. This is largely due to the fact that the active substance, which is part of the drug, affects the vessels, provoking their contraction. In addition, the drug affects the pulse rate. For this reason, Berodual should not be taken for inhalation during pregnancy in the 3rd trimester for women suffering from tachycardia and arrhythmia.

With caution it is prescribed for arterial hypertension. Contraindication is individual intolerance to the components of the drug. It is undesirable to use "Berodual" during pregnancy in the 3rd trimester. This is due to the fact that it can affect the muscle tone of the uterus, which can negatively affect the delivery process.

Side effects and overdose

The negative effects of the drug are associated with a high level of activity of the main components, if used for inhalation. In addition, the drug may cause local irritation. This side effect is typical for all types of inhalation therapy. Among them, it is necessary to highlight such as:

• headache;
• dry mouth;
• dizziness;
• cough;
• pharyngitis;
• tachycardia;
• nausea and vomiting;
• nervousness.

In addition, other side effects may occur when using the drug during pregnancy. On the part of the cardiovascular system, this can be atrial fibrillation, arrhythmia, ischemia, and increased pressure. In the respiratory tract, there may be irritation of the pharynx, swelling, bronchospasm.

When using the drug, there may be an increase in intraocular pressure, the development of glaucoma, blurred vision, double objects, swelling of the cornea. The immune system may react to the drug with an increase in sensitivity or anaphylactic manifestations.

From the side of the nervoussystem, such disorders as excessive overexcitation, trembling of the limbs, nervousness can be observed. This is especially evident when performing small movements. In the metabolic system, the drug may cause a decrease in the level of potassium in the blood.

The drug can provoke the development of stomatitis, deterioration of intestinal motility, constipation or diarrhea, and swelling in the oral cavity. Rashes, itching or local swelling may appear on the skin. The drug may affect the urinary system. This manifests itself in the form of a delay in the process of urination.

The most likely signs of an overdose are:

• increased difference between diastolic and systolic pressure;
• angina;
• feeling of heat and flushing of the skin;
• increased bronchial obstruction;
• tachycardia;
• metabolic acidosis.

Overdose is due to excessive intake of the active substance into the body. This may cause dry mouth or visual impairment.

Treatment for overdose is symptomatic and includes the use of sedatives as well as tranquilizers. In case of severe intoxication of the body, intensive care measures are required.

Special Instructions

Treatment must be carried out under constant medical supervision. It is recommended to do this in a hospital setting. The organization of treatment at home is possible only after consultation with the doctor. The solution for inhalation is prescribed only inin the event that an aerosol cannot be used or a higher dosage is required.

The dose of the drug is selected strictly individually, and it depends on how acute the attacks are. In general, therapy is initiated at the lowest acceptable dosage and discontinued only after a marked reduction in symptoms has been achieved.

Use Berodual during pregnancy in the 2nd trimester very carefully so as not to provoke the occurrence of side effects. The patient must be informed of the unexpected, rapid increase in dyspnea. In this case, you should definitely consult a doctor.

It is worth remembering that women with asthma should use the drug only as needed. With mild chronic pulmonary obstruction, symptomatic therapy can be much more effective than the regular use of Berodual. Additionally, anti-inflammatory therapy may be required.

Proper use of the medicine is essential. To prevent the solution from getting into the eyes, when using a nebulizer, inhale it through the mouthpiece. In its absence, a mask that fits snugly to the face should be used. Especially care should be taken to protect the eyes of patients with a predisposition to the development of glaucoma.

Use the medicine with extreme caution during breastfeeding, as it passes into milk.

The drug should be stored in a place protected from the sun and out of the reach of children whenroom temperature. The shelf life of the drug is 5 years. Do not use it after the expiration date indicated on the package.

Drug Interactions

Since the active component of Berodual is a combination of a beta-agonist and an m-anticholinergic, when combined with other drugs, a decrease in the bronchodilator effect is possible.

When used simultaneously with glucocorticosteroids, there may be an increase in the effectiveness of therapy. In the case of combination with anticholinergic drugs, side effects may increase, and a more pronounced effect of Berodual is also observed.

When used simultaneously with Digoxin, the risk of arrhythmia increases. If you need such a combination of drugs, you need to constantly monitor the level of potassium in the blood serum.

Analogues

If there are contraindications for the use of "Berodual" for inhalation during pregnancy in the 2nd trimester, you need to consult a doctor who will select analogues of the drug. There are several medications that have a similar therapeutic effect. These should include such as:

• Berotek;
• "Duolin";
• Ventolin;
• Pulmicort.

Since Berodual has a strong effect on the functioning of the cardiovascular system, in the presence of heart disease it is advisable to replace it with Pulmicort. This medicine belongs to hormonal drugs, and it contains a steroid component. When the drug is used, the effect isspecifically to the adrenal glands. The drug affects the cellular structures and contributes to the normalization of metabolic processes.

The effectiveness of Pulmicort is several times higher. However, it has no effect on the heart muscle. The process of preparing the solution is exactly the same as that of Berodual. It is also diluted with saline. The number of treatment procedures should be no more than 2 per day. The duration of treatment is also reduced due to its high effectiveness.

Application reviews

Women in their reviews of "Berodual" during pregnancy in the 1st trimester say that it is impossible to use the drug during this period. However, in some cases, it is still prescribed, given the benefits and possible harm. The components of the drug have a high ability to suppress the work of receptors. Easy to use, just add to a measuring cup and mix with saline.

In case of respiratory diseases, Berodual is often prescribed during pregnancy. Reviews of doctors about this remedy are mostly positive, as it helps to prevent the occurrence of repeated attacks in bronchitis and bronchial asthma. In addition, this drug is considered one of the most affordable.

It can be safely used for treatment during childbearing in the second trimester. The first and last weeks are considered an absolute contraindication, since the active substances affect the development of the fetus and the delivery process.

However, ifthe disease is very difficult, then the doctor may prescribe "Berodual" in this period, as it will help prevent the occurrence of complications that are of great danger to the woman and the child. Many pregnant women who used this drug speak only positively about it. They say that its active ingredients do not affect the development and he alth of the fetus.

According to the instructions for use, "Berodual" has many limitations and side effects. However, most contraindications are relative, so you can use the drug, but you need to be careful. It is necessary to adhere to all the recommendations of the doctor in order to avoid various side effects and complications. Before using the medicine directly, you should consult a doctor.