The appointment of "Cytoflavin" during pregnancy is due to the need to provide comprehensive assistance to the work of the body. This includes antioxidant protection, vitamin therapy, immunomodulatory properties of the drug and its beneficial properties to improve metabolic processes. It is effective in restoring the nervous system. The purpose of this drug is due, most often, to signs of fetal hypoxia, impaired uteroplacental blood flow. In order to minimize the risks posed by this phenomenon, the Cytoflavin drug is prescribed.
The annotation for this medicinal product in the form of tablets contains an indication of the original composition, which includes:
- Vitamin B2 (riboflavin) - 0.005 g and PP (nicotinamide) - 0.025 g.
- Riboxin (inosine) - 0.05 g.
- Succinic acid - 0.3 g.
Pills are round in shape, painted bright red, so worthpay attention to the fact that among the auxiliary components there are dyes: tropeolin-O and azorubine. In addition, calcium stearate, povidone, propylene glycol, polysorbate, hypromellose are used as ingredients that allow the tablet to retain the shape and beneficial properties of the active ingredients.
If "Cytoflavin" is prescribed intravenously, the instructions for use contain information that the number of main components is different. So, riboflavin in it is 2 mg, nicotinamide - 10 mg, inosine - 20 mg, succinic acid - 100 mg.
In the pharmacy network you can find two forms of release of the drug "Cytoflavin", depending on the prescribed course of treatment, you can choose the most suitable option:
- Pills that are enteric-coated.
- Solution for intravenous injection.
If Cytoflavin was prescribed during pregnancy, then you can purchase 5 and 10 ml ampoules at the pharmacy, including the form of an insulin vial with the same dosage. As auxiliary components, the manufacturer indicates water, sodium hydroxide and meglumine. The color of the solution is dark yellow, transparent. The presence of sediment at the bottom of the ampoule is not allowed. It is also recommended to store them in a dark place at a temperature of +15 to +25 degrees.
Pills are packed in cardboard boxes, in a blister - 10 pcs. In retail, two types of the drug are offered with quantities of 50 and 100 pcs. In shape they are round, biconvex, in the section you can seethat consist of two layers of yellowish color.
The role of the main components
The appointment of "Cytoflavin" during pregnancy is necessary to eliminate signs of fetal hypoxia. Preparations of this type are selected strictly on the recommendation of a doctor. The main components of "Cytoflavin" are vitamins, so it is worth considering the effect of each separately.
Nicotinamide during active biochemical reactions and transformations activates enzymes that depend on it and help deliver oxygen to cells. Vitamin B3 is involved in the synthesis of ATP (adenosine triphosphoric acid), normalizes cellular respiration.
The flavin coenzyme - riboflavin - activates vital processes for cells that relate to the redox reaction of the tricarboxylic acid cycle (it is also called the Krebs cycle for short).
Purine derivative - inosine - is considered a precursor of ATP, is involved in the synthesis of such nucleotides as NAD and FAD. Participates in the activation of some enzymes involved in the Krebs cycle. This also includes succinic acid, which is an indispensable participant in the metabolic processes occurring inside the cell. This component synthesizes energy, due to which cells receive more oxygen, activating electron transport in mitochondria.
The complex of these components is aimed at stimulating intracellular respiration. It is fully justified that Cytoflavin is prescribed during pregnancy if there are signs indicating fetal hypoxia.
How does it work?
The main advantage of using Cytoflavin during pregnancy is its rapid absorption by the body. Its main components are rapidly absorbed through the gastrointestinal tract. Decay products are excreted through the kidneys with urine. Nicotinamide and riboflavin penetrate the placental barrier, which is quite characteristic of the vitamin group. In a word, they contribute to the normal functioning of the cell, reducing the need for neurons in oxygen molecules. The drug allows cells to accumulate energy, improving their saturation with blood oxygen, thereby limiting the area of ischemic damage to fetal brain tissues.
Succinic acid breaks down already 30 minutes after ingestion. The maximum concentration in the blood of inosine is 5 hours, nicotinamide - 2 hours, both components retain their effect for another 4.5-5.5 hours. Riboflavin is distributed unevenly in the body. Its highest content is noted in the myocardium, kidneys and liver.
Doctors recommend diluting the contents of the ampoule for injection with 5% glucose solution. In this case, it is possible to avoid the onset of side effects and discomfort caused by succinic acid. As part of complex therapy, there is a rapid onset of the effect and the preservation of positive dynamics.
Indications for use
The drug in tablets "Cytoflavin" is indicated for the following symptoms: increased fatigue, irritability. If we talk about such signs as a violation of the braincirculation (in acute form), vascular encephalopathy, then preference is given to a solution for intravenous injection. As a rule, Cytoflavin droppers are prescribed when a pregnant woman is treated in a hospital with a diagnosis of fetal hypoxia.
In other cases, indications for the use of the drug are: a consequence of a stroke, post-anesthetic period, neurasthenia, toxic encephalopathy (including combined genesis). The main condition for the use of the drug while a woman is in position is the absence of allergic reactions to the components of the drug. However, there are clarifications that the drug has not been tested separately for this category of patients.
Those who have encountered such a diagnosis as fetal hypoxia know why Cytoflavin is prescribed during pregnancy, moreover, they have experienced its positive properties. Lack of oxygen adversely affects blood circulation, respiratory functions, and metabolism between mother and fetus. Often there is a lack of important components that are involved in biochemical processes. As a rule, it is vitamins that make up for such a deficiency and contribute to the restoration of the body's natural functions. The sooner treatment is started, the higher the chance of complete recovery of affected cells.
Without a doctor's prescription, the use of the drug is not recommended. Since only he can establish the correct treatment regimen. You can check the annotation in the instructions, where the dosage is indicated - 2 tabletstwice a day. The interval between them should not exceed 10 hours. The last tablet is taken no later than 18 pm.
Regarding instructions before or after meals. The manufacturer recommends adhering to the interval 30 minutes before the start of a meal, without chewing, drinking plenty of clean drinking water. However, given the fact that the composition contains succinic acid, doctors still recommend taking the pills with meals. The course of treatment is long, up to 25 days. If we talk about intravenous injections, then as prescribed by a doctor, 5-10 days. You can start taking this drug again 1 month after the end of the previous course.
In case of intolerance to the components of the drug, it is recommended to refrain from using it. The manufacturer also pointed out the inadmissibility of its appointment during the period of breastfeeding in the form of intravenous injections. Pregnant women who control blood glucose levels should be given special attention during treatment.
Doctors recommend reporting any abnormalities in the treatment process. It is noted that while driving a car there are no contraindications for the use of Cytoflavin.
Adverse reactions and overdose
Patients who followed the instructions for the use of "Cytoflavin", reviews about the drug are mostly mostly positive. With regard to intravenous injections, doctors recommend making sure that the process of administering the drug is slow.This will avoid the discomfort that succinic acid causes. In the case when the drug is administered quickly, the patient may feel a sore throat, shortness of breath, a flush of heat (sensation of heat in the body). Allergic reactions to the components of the drug are not excluded.
The least common side effects as a result of the appointment of a Cytoflavin dropper. However, it should be borne in mind that after the injection, a hematoma may form. Therefore, immediately after the end of the procedure, it is recommended to bandage the injection site with a bandage. To avoid adverse effects on the gastrointestinal tract, doctors advise to carry out the procedure after eating, on a full stomach. At the moment, there have been no cases of drug overdose.
Sometimes the simultaneous administration of "Cytoflavin" in conjunction with other dosage forms is shown. In practice, it has been proven that it goes well with antioxidants, as well as drugs that improve the process of hematopoiesis. Due to the fact that the composition includes succinic acid, brain cells receive decent protection from the adverse effects of the external environment.
Among those drugs that are not recommended to be used simultaneously with "Cytoflavin" - antibacterial and streptomycin. It reduces their active properties and the effect of the application may be negative.
You can often find questions about why Cytoflavin is needed for pregnant women. It is prescribed strictly according to the indications that are associated with the establishment of the fact of a lack of oxygen and the presence of signsfetal hypoxia. Timely treatment allows you to quickly restore the body and make up for the deficiency of useful components in the body of the mother and child.
During the course of treatment, there are no restrictions in terms of performing work duties related to the management of transport, driving mechanisms.
Feedback from patients and doctors
Questions like "what is Cytoflavin for" arise when the doctor does not comment on the advisability of prescribing this drug. Fortunately, there is an opportunity to get feedback from those who have already experienced the benefits of its use. Pregnant women who were previously prescribed Cytoflavin note that it was prescribed during hospital treatment. And this is no accident, as it has a tangible and quick positive effect. Under the conditions of round-the-clock control within the walls of a medical institution, a doctor can adequately assess progress or take timely measures to eliminate adverse side reactions. They, as a rule, come down to individual intolerance to the components of the drug.
Women who were prescribed "Cytoflavin" in a dropper during pregnancy, speak positively about its tolerance. In general, no adverse reactions are felt, and the activity and he alth of the fetus are noticeably improved. Moreover, a pregnant woman feels a surge of energy. Already seven days after the start of the course of treatment, uteroplacental blood flow acquires a positive trend. Due to which the pregnancy continues in a natural way, anddelivery is on time.
If the doctor has prescribed Cytoflavin to be administered intravenously, the instructions for use must be studied not only by the doctor, but also by the patient. This is especially true for those who like to look for substitutes or analogues for a particular remedy. Moreover, drugs with similar properties may not contain one or another component, which is an advantage for choosing this particular dosage form. Patients' comments about the need to use an analogue often boiled down to choosing it because of its lower cost. However, this should not be done without a doctor's recommendation.
Medical practice of using this drug shows that it is much more effective as part of complex therapy than if it is used as the main method of treatment. Thus, the diagnosis of the placenta after childbirth revealed facts confirming the positive effect of the use of Cytoflavin. There are also significantly fewer foci of hypoxia damage to the membranes. Moreover, it is noted that the Apgar score of a newborn is 0.5 points higher than in children whose mothers were not prescribed this drug in case of a pathological course of pregnancy.