"Josamycin" during pregnancy: composition, instructions for use, contraindications, reviews

2024 Author: Priscilla Miln | [email protected]. Last modified: 2023-12-16 00:21

The expediency of using various kinds of drugs by pregnant women always raises many questions. In particular, future mothers are very worried if the doctor prescribed them antibiotics. Of course, such drugs for the fetus cannot be useful by definition. However, sometimes it happens that taking a medicine does less harm to the unborn child than the mother's disease itself, for the treatment of which it is prescribed. For example, quite often, doctors prescribe Josamycin to women who are expecting a baby. It is considered relatively safe to take this medication during pregnancy.

Composition and release form

This medicine belongs to the group of antibiotics officially approved for use during pregnancy. In our country, the trade name of "Josamycin" is "Vilprafen". That is what is written on the package with this drug. This medicine is produced in the form of white biconvex tablets intended for oral administration. The product is delivered to pharmacies and clinics in regular blisters.

The main active ingredient of this medicine is actuallyjosamycin. This substance is a fine white powder, highly soluble in alcohol and ether. This component is produced by actinomycete bacteria. Vilprafen also contains several additional substances - polysorbate 80, cellulose, silicon dioxide, magnesium stearate, etc.

Features of the drug

Getting into the patient's body, the active substance "Josamycin" inhibits the translocation of the protein of harmful bacteria. This medicine can destroy, for example, chlamydia, mycoplasma, legionella, Neisseria. At the same time, the advantages of this drug include the fact that it has practically no harmful effects on the microflora of the intestines and stomach. Also, the undoubted advantage of this medicine is that it does not cause resistance in patients.

During pregnancy, "Josamycin" can be taken, but only in accordance with the recommendations of the attending physician. The disadvantage of this antibiotic, like almost any other, is that it is able to cross the placenta and also enter breast milk.

Josamycin reaches its maximum concentration in the patient's body after 1-2 hours after ingestion. This drug is excreted in bile and urine.

When it can be prescribed to pregnant women: diseases of the urogenital tract

Expectant mothers doctors usually prescribe Josamycin when they have such diseases as:

• Chlamydia is a sexually transmitted disease that is dangerous for the development of pathologies in the fetus, oftenleading to miscarriage.
• Mycoplasmosis is also a sexually transmitted disease, dangerous in that it can cause pregnancy to stop.
• Syphilis is a disease that can lead to miscarriage, infection of the fetus, the development of pathologies in it.
• Ureaplasmosis is a disease transmitted both sexually and by contact, fraught with infection of the fetus and miscarriage.
• Gonorrhea is a disease leading to intrauterine death of the fetus, inflammation of the fetal membrane, placental insufficiency.

Use for ENT diseases

Also, this medicine can be prescribed to pregnant women if they have such ailments as:

• acute bronchitis;
• pharyngitis;
• sinusitis;
• otitis media;
• laryngitis;
• whooping cough;
• tonsilitis;
• psittacosis and some others.

All these diseases are not particularly dangerous. But all of them, unfortunately, can harm the fetus. With these ailments, a pregnant woman can begin premature birth. Also, such diseases in some cases even lead to the development of pathologies in the fetus or infection of the child when moving through the genital tract.

Indications for pregnancy: skin infections and ophthalmic ailments

With such diseases, "Josamycin" can also be prescribed to expectant mothers. Ailments of this group can lead to complications during pregnancy and harm the fetus. Prescribed "Josamycin" during pregnancy for treatment:

• lymphangitis;
• pyoderma;
• furunculosis;
• dacryocystitis;
• bleopharitis.

"Josamycin" during pregnancy: can it harm the fetus

As noted above, this medicine, among other things, is able to cross the placenta. As a result of clinical studies regarding the possibility of causing harm to the fetus by this agent, no negative effects have been identified. However, Josamycin can still enter the child's body. Therefore, it should be prescribed to a pregnant woman only by a doctor and only after he has assessed all possible risks.

Diseases in which pregnant women can be prescribed this medicine, as you can see, there are many. But this does not mean at all that when diagnosing any of these ailments, the doctor will immediately prescribe the antibiotic Josamycin to the expectant mother. During pregnancy, this remedy in any case can be harmful. Therefore, at first the doctor, most likely, will still try to use some remedy that is safer for the fetus to treat the disease. Josamycin is usually given to pregnant women only if the use of more gentle drugs does not give the desired results.

Using the drug by trimesters

In the 1st trimester, "Josamycin" during pregnancy is usually not prescribed to women. It is highly undesirable to use it at this time. Doctors prescribe it to women in most cases not earlier than the 10th week of gestation. Before this time for treatmentserious diseases, such as chlamydia, usually use a milder "Azithromycin". Treatment of not such dangerous ailments - ureaplasmosis or, say, mycoplasmosis is postponed to a later date.

In the 2nd trimester during pregnancy, "Josamycin" is prescribed to women quite often. However, during this period, doctors prescribe it with extreme caution. Absolutely calmly, this medicine can be taken only from the 22nd week of pregnancy. At this time, all the main systems of the child are already reaching the final stage of their formation. Accordingly, the remedy cannot cause much harm.

In the later stages, there is practically no chance that this drug will have a negative effect on the fetus. Therefore, Josamycin can be taken during pregnancy in the 3rd trimester almost without fear. Cases of the negative impact of its use on the bearing and development of the fetus at this stage have not been identified.

Medication dosages

Of course, the instructions for "Josamycin" during pregnancy (and in any other situations) should be carefully studied. Expectant mothers should take this remedy exclusively in the manner recommended by the doctor. Dosages prescribed by a specialist in the treatment of "Josamycin" must be observed exactly. Doctors usually choose a therapy regimen using this drug, taking into account the characteristics of this particular disease. For example, with chlamydia, the course of treatment with this remedy is usually 14 days. With mycoplasmosis, "Josamycin" is drunk for 10 days. Also, when choosing dosages, doctorstake into account the woman's weight, and, of course, the gestational age.

How to take it right

Drinking Josamycin tablets (including during pregnancy) is supposed to be between meals. In this case, they will affect the body most effectively and gently. It is best to swallow these tablets whole with plenty of water.

What side effects can cause

Familiarization with the instructions for the use of "Josamycin" during pregnancy should in no case be neglected. This medicine belongs to the group of modern drugs that have a minimal harmful effect on the patient's body. No side effects in pregnant women, as in any other patients, are usually observed with this remedy. However, sometimes this medicine, of course, can have a negative effect on the body of women. For example, pregnant women treated with this remedy may experience:

• heartburn, nausea, diarrhea;
• urticaria;
• hearing impairment;
• dysbacteriosis, candidiasis.

Sometimes patients taking Josamycin also experience abdominal pain. Loss of appetite is also one of the side effects that this drug can cause.

Contraindications

Doctors prescribe the drug "Josamycin" to pregnant women with caution. In some cases, this medicine, like any other, cannot be prescribed to expectant mothers at all. Contraindications to therapy using this agentare:

• individual intolerance to any components;
• serious impairment of kidney and liver function;
• Hypersensitivity to macrolides.

Analogues of the drug

In some cases, instead of this remedy, doctors may prescribe to patients, including pregnant women, drugs similar in therapeutic effect. Analogues of "Josamycin" are:

• "Sumamed";
• "Clarithromycin";
• "Azitral";
• "Amoxicillin".

The active ingredient in all of these drugs is josamycin. They can also be prescribed for the treatment of various kinds of diseases for pregnant women. However, changing "Josamycin" to any of these funds on your own, of course, is not worth it. In pregnant women, this can lead to unpredictable consequences. Women who are expecting a baby can use any substitute for this drug only after consulting with their doctor.

Should I take Josamycin during pregnancy: drug reviews

Expectant mothers have an ambiguous opinion regarding the effectiveness of this remedy. Some pregnant women with various kinds of infectious diseases, it helps well. For others, this tool, judging by the reviews available on the Internet, turned out to be completely useless. In some cases, as expectant mothers note, this medicine helps against all kinds of infectious diseases only after passing two courses.

To the absolute pluses of thisthe drug, many women attribute the fact that it can indeed be considered safe for the fetus. In the 3rd and 2nd trimester during pregnancy, "Josamycin", according to many patients, really does not have any harmful effects on the child. Children of mothers who took this drug are born he althy. As many patients note in their reviews on the Web, their babies did not develop an allergy to antibiotics.

Expectant mothers consider another plus of this medication to be the softness of its action. Judging by the reviews from the Internet, this medication almost never causes side effects.

Combinations with other drugs

Sometimes "Josamycin" (during pregnancy, including) can be prescribed simultaneously with other drugs. It is not very useful for expectant mothers to take, of course, any medicines. And it is up to the attending physician to decide which combinations of drugs can be used and which cannot. In any case, the doctor must be aware of what other drugs his patient is taking at the time of discharge of Josamycin.

On the microflora of the gastrointestinal tract, this drug has, as already mentioned, not a very strong effect. But still it belongs to antibiotics and in this regard it cannot be useful for the stomach and intestines. Therefore, doctors at the same time quite often prescribe Linex and other similar drugs to pregnant women, which include lactobacilli. Also, of course, in combination with Josamycin, expectant mothers can take differentkind of vitamins. Means with lactobacilli are useful in that they are able to restore the microflora disturbed by the antibiotic. Vitamins also contribute to the rapid strengthening and restoration of the body in the treatment of this medicine.

Can I take during lactation

Pregnant patients may be prescribed this drug in some cases. But during breastfeeding, a woman will still have to refuse treatment with this remedy. Nursing mothers should not be given Josamycin.

In rare cases, treatment with this particular drug becomes a necessary procedure. If Josamycin cannot be replaced by any other drug, the baby will most likely have to be switched to artificial feeding.

Children are usually prescribed this drug no earlier than 3 months of age. It is prescribed for small patients under 14 years of age at a dosage of 40-50 mg per 1 kg of body weight.