2024 Author: Priscilla Miln | [email protected]. Last modified: 2023-12-16 00:21
Environmental pollution, eating low-quality food, exposure to constant stress do not have the best effect on women's he alth. Every year more and more women are faced with the inability to become pregnant and bear a he althy baby. The causes of these complications can be many diseases. Some of them are not amenable to treatment, and families have to resort to the services of surrogate mothers, in vitro fertilization. But thanks to progress in modern medicine, most of these problems can be solved with the help of special drugs. One of them is Duphaston. This drug has proven itself from the best side, in medical practice there are a large number of women who have been helped by Duphaston to become pregnant and give birth to he althy babies. What is the essence of the drug? We will talk further about how conception occurs on Duphaston.
Female sex hormones
To understand how Duphaston affects conceptionchild, you need to understand the mechanism of the female reproductive system. The menstrual cycle is formed by two main female hormones - estrogen and progesterone. Progesterone is produced by the ovaries and adrenal glands during the second phase of the menstrual cycle and plays a critical role in the processes of fertilization, gestation and the menstrual cycle.
In the first half of the cycle, there is an increased production of estrogen, with its help the follicles mature, the dominant one stands out among them, which will later become an egg. The second half of the cycle begins with ovulation, during which the follicle ruptures. Then the progesterone content reaches its maximum values, and the egg leaves the follicle in anticipation of the sperm. At the site of rupture of the follicle, the formation of a corpus luteum occurs, it maintains the desired level of progesterone in the blood. Enough progesterone at this stage is very important and has a number of goals:
- the structure of the uterine wall becomes looser, ready to receive a fertilized egg;
- the uterus becomes calmer, does not shrink, protecting the fetus from rejection;
- mammary glands are already beginning to prepare for milk production, their shape and volume are changing;
- the emotional sphere of a woman is at rest, it becomes easier to regulate emotions;
- The uterus expands according to the needs of the fetus.
What role does progesterone play
It is on this substance that the whole process of bearing a child depends from fertilization of the egg tobirth. Lack of progesterone leads to the inability to become pregnant or bear a fetus. If a woman cannot get pregnant for a long time, she has menstrual irregularities or has previously had miscarriages, after a complete examination and confirmation of the lack of this hormone, the gynecologist prescribes Duphaston. So, how does Dufaston affect conception, what role does it play in this sacrament?
Active ingredients
In infertility, this drug is used as an artificial replacement for the "pregnancy hormone". The main active ingredient of the product is dihydrogesterone, in its structure it is as close as possible to natural.
Previously, similar artificial substances were obtained from male sex hormones. Of course, taking such drugs provoked a huge number of side effects: male-type hair, a change in the timbre of the voice, hormonal failure. Knowing about this experience of past generations, women today are afraid of taking hormonal drugs, but now the situation is completely different.
Modern technologies have made it possible to obtain a new generation drug, it does not have such a detrimental effect on a woman's hormonal background. "Dufaston" completely compensates for the lack of progesterone, even with a significant lack of it.
However, how much to drink "Dufaston" to get pregnant, only the attending physician can say. Dosage and duration of administration is calculated individually for each patient. That is why you should neverfocus on the experience of women who "Dufaston" helped to get pregnant earlier.
Indications for admission
There are clear indications for the appointment of "Dufaston":
- endometriosis - a disease in which there is an overgrowth of uterine tissue, there are delays in menstruation;
- infertility due to lack of lutein;
- threatened miscarriage due to insufficient progesterone levels;
- menstrual irregularity;
- uterine bleeding;
- hormonal failure after surgery.
In other words, even if you have an obvious hormonal failure, a menstrual cycle disorder, the self-administration of Duphaston is unacceptable. Only a qualified doctor, after a complete examination confirming that infertility is a consequence of disturbances in the production of progesterone, prescribes Dufaston as a replacement therapy.
Contraindications for taking
Like any drug, Duphaston has contraindications for use:
- hypersensitivity to ingredients;
- chronic renal failure;
- signs of allergy: itching, peeling, rash;
- lactation period.
Side effects when taking
Side effects when using Duphaston:
- dizziness;
- headache;
- anemia;
- nausea and vomiting;
- vaginal bleeding;
- liver disorders;
- itching, urticaria, swellingQuincke;
- brown discharge during pregnancy.
"Dufaston": instructions for use when planning pregnancy
In order for the drug to have the desired effect, it is necessary to correctly calculate the dosage and the regimen for its administration. Is it possible to get pregnant after "Duphaston"? Definitely, you can. However, there is no universal drug treatment regimen. There are no clear instructions for the use of "Duphaston" when planning a pregnancy. It is forbidden to use for yourself the appointments of another patient or self-medicate. The instructions for use offer only general recommendations, so only a doctor can competently say how to drink Duphaston for conception in each specific case.
If the drug is taken at the wrong time of the cycle, it acts as a contraceptive. Synthetic progesterone eliminates infertility only if the cause is its lack.
Often "Dufaston" is prescribed for the second part of the cycle: the day after ovulation and before the onset of menstruation. Cancellation occurs only in the absence of pregnancy. To make sure of this, you need to wait for your period or take a pregnancy test, you can also donate blood to determine the level of hCG. If you stop taking the drug before pregnancy is detected, a sharp jump in the hormone will provoke starvation and rejection of the fetus.
To achieve the maximum effect, "Dufaston" is prescribed for six months. If treatment continues for more than a year without results, then it is necessary to discuss withdoctor to change therapy and undergo a re-examination.
How to take
As mentioned, treatment regimens are individual, but there are general principles for prescribing the drug. With infertility caused by endometriosis, 10 mg is prescribed three times a day continuously or on days 5-25 of the cycle.
If luteal insufficiency caused infertility, 10 mg of Duphaston is prescribed on days 14-25 of the cycle. Interruption of treatment within six cycles is contraindicated. After therapy, it is recommended to continue treatment in the first 2-3 months after conception.
If there is a threat of miscarriage, take 40 mg of Duphaston at a time and 10 mg every 8 hours until symptoms disappear.
In case of failure of the menstrual cycle, 10 mg is prescribed on days 11-25 of the cycle.
After the onset of pregnancy, it is forbidden to abruptly stop taking the drug, since during the normal course of pregnancy, the hormone level decreases gradually, when the corpus luteum transfers its functions to the placenta. In the process of planning a pregnancy, Duphaston corrects the level of progesterone and promotes implantation of the embryo.
When examining, choose the right time for testing, as the level of progesterone varies depending on the phase of the cycle. Donate blood in the middle of the second phase, it is ideal to choose a day between ovulation and the onset of menstruation. If your periods are irregular, monitor your cycle by measuring your basal body temperature every morning. If this is not possible, take the test twice at the estimated time with an interval of a couple of days.
Should I continue therapy after pregnancy?
During the treatment with Duphaston, synthetic progesterone creates conditions in the uterus that are favorable for the attachment and development of the embryo. Those who "Dufaston" helped to get pregnant, in their reviews note that after the onset of the long-awaited result, it is impossible to relax and stop treatment. On the contrary, therapy is gaining momentum. Immediately inform your doctor about conception, based on your condition, he will decide whether to continue treatment or change tactics.
The effect of "Duphaston" at the stage of carrying a pregnancy is radically different than when planning. As a result, dose adjustment is required. Progesterone affects the muscles of the uterus, prevents its contraction, reduces tone. Thanks to this hormone, the woman's body provides conditions for bearing a fetus, minimizing the risk of miscarriage.
The active ingredients of the drug relax the intestines, prepare the breast for lactation, pregnancy is put in first place in the physical and emotional aspects. It is important that Duphaston helps not only with a lack of progesterone during conception, but also with the threat of miscarriage in the early stages of pregnancy.
If pregnancy occurs due to the action of Duphaston, the expediency of its further intake, duration and doses are individually negotiated with the doctor. He will solve these issues after undergoing ultrasound and tests.
When is it time to cancel?
By 18-20 weeks, progesterone levels becomestable, its production is taken over by the placenta, and taking the drug becomes inappropriate. At week 20, the placenta is able to independently regulate hormonal levels and maintain pregnancy.
But even now it is impossible to abruptly stop taking Duphaston. The body must gradually learn to replenish progesterone reserves on its own. Abrupt withdrawal of the drug will lead to a drop in the concentration of the hormone in the blood, starvation of the placenta and an increase in the tone of the uterus.
If the doctor insists on an appointment
If your doctor insists you start taking Duphaston after ovulation to conceive, don't resist it. This drug, despite its synthetic nature, is safe for women and children and has been proving its effectiveness for many years. Many women in Russia and abroad have become mothers thanks to this medication. Your main task is to find a qualified specialist who can choose an individual regimen for taking the drug, and trust him.
To protect yourself from side effects, you need to take the medicine only after consulting a doctor, a thorough examination of the body and in strict accordance with the doctor's prescriptions. With proper use of the drug, a positive result is guaranteed. It can be said unequivocally that those women whom "Duphaston" helped to get pregnant, adhered to just such tactics of behavior.
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